However, if the side effects last longer than . It can also interact with certain supplements as well as certain foods. For primary high cholesterol, Zetia is FDA-approved for use in adults and children* to decrease levels of: For this purpose, Zetia is used with a low-cholesterol diet. Note: Zetia isnt approved to lower these types of cholesterol: Cholesterol is measured in several ways. They may want to select a different treatment option for you. But it may be a sign that your liver isnt working as well as it should. Lipitor ( atorvastatin) and Zetia ( ezetimibe) are used to lower cholesterol levels in the blood. (For more information on the specific conditions Zetia can treat, see the Zetia uses section.). Zetia may cause mild side effects other than the ones listed above. If you miss a dose of Zetia, you can take your missed dose as soon as you remember. Zetia is FDA-approved to treat certain forms of high cholesterol in adults and children. Ezetimibe may be used alone or with other drugs (such as "statins" or . However, side effects are generally mild and go away as the body adjusts to the medication. For this purpose, Zetia is used with a low-cholesterol diet (but with no other drugs) in adults and in children ages 10 years and older. Postural Orthostatic Tachycardia Syndrome (POTS) is a blood flow disorder that causes a sudden spike in heartbeat with no change in blood pressure when going from a horizontal or seated to a standing position. After stopping Zetia treatment, their liver enzymes levels went back down. Zetia is a lipid-lowering compound used to treat high cholesterol.Common side effects of ezetimibe include diarrhea, abdominal pain, back pain, joint pain, muscle aches, and sinus infection ().. Serious side effects of ezetimibe include hypersensitivity reactions (including angioedema - swelling of the skin and underlying tissues of the head and neck - that can be life-threatening), skin rash . stuffy nose. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. Zetia has a well-documented safety profile. This may be caused by genetics, smoking, not getting enough physical activity, or eating too many foods that are high in cholesterol. But its not clear whether this side effect occurred in studies. 6. Within 4 to 12 hours of oral administration, a single 10-mg dose of Zetia reaches peak plasma concentrations of 3.4 to 5.5 ng/mL. The Food and Drug Administration (FDA) approves prescription drugs such as Zetia to treat certain conditions. For example, in studies, some people had to stop taking the drug because their liver enzyme levels increased. Is it harmful to take a coenzyme Q10 (CoQ10) supplement along with Zetia to help prevent muscle-related side effects? Your doctor may stop your Zetia treatment if it isnt safe or effective for you. Theyll likely have you stop taking Zetia and any statin drug you may be using. It can develop suddenly or gradually over time. However, skip your missed dose if its almost time for your next dose. Zetia can cause mild or serious side effects. Porphyrias are rare, mainly genetic disorders that affect the body's ability to make hemoglobin. This part of the nervous system controls functions that we don't actively control, such as heart rate, blood pressure, perspiration, and temperature. For this purpose, Zetia may be used alone or with fenofibrate. What causes POTS? Symptoms of liver damage include: If you have any of the above symptoms of liver damage, tell your doctor right away. Its not known if its safe to take Zetia while breastfeeding or if the drug passes into breast milk. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Fenofibrate belongs to the fibrate drug class. Zetia is FDA-approved to treat mixed high cholesterol when used with fenofibrate. (2018). In clinical studies that lasted 8 weeks, Zetia was compared with a placebo (a treatment with no active drug). People with HoFH have high levels of LDL (bad) cholesterol. For more information and to find out if youre eligible for support, call 800-727-5400 or visit the program website. . No, clinical studies havent shown Zetia to affect blood pressure. This section doesnt contain all drugs that may interact with Zetia. If you have questions about weight changes while using Zetia, talk with your doctor. Or they may recommend that you stop taking the medication. Dizziness is a rare side effect of taking Zetia. Brand-name medications usually cost more than generics. If you have liver problems, your liver may not work properly to remove medications such as Zetia from your body. 5.8k views Answered >2 years ago. Some may be a better fit for you than others. It may take about 2 weeks for your cholesterol levels to improve after you start taking Zetia. Your child can take Zetia with or without food. The following lists contain some of the key side effects that may occur while taking Zetia. Increased liver enzymes can be a sign of liver damage. While there's no cure, several treatments and lifestyle changes can help manage the symptoms of POTS. If youre using Zetia while sexually active with a female who could become pregnant, talk with your doctor about your birth control needs. Phase IV trials are used to detect adverse drug . The dose of Zetia used for children is the same as the adult dose. Cholesterol can also be found in foods such as eggs, cheese, and meat. But reviews and complaints about medications, including Zetia, may not be as reliable as other types of consumer reviews. Clinical studies have shown Zetia to be effective for treating homozygous sitosterolemia when used alone. Yes, there are a few. The Benary's Giants have large, double blossoms, 4 to 6 inches across, available in a rainbow of . For information on the effectiveness of Zetia, see the Zetia uses section below. Zetia contains the active drug ezetimibe. Zetia comes as a tablet that you swallow. Fenofibrate is a drug used to lower your triglyceride levels. Study on Ezetimibe Yielded Disappointing Results: Another reader wrote us shortly after learning of the results of a study that raised questions about ezetimibe: Q. Less commonly, taking Zetia may lead to serious side effects. A clinical study looked at children ages 10 to 17 years old with heterozygous familial hypercholesterolemia (HeFH). In certain conditions (such as when traveling), you may temporarily store Zetia at temperatures of 59F to 86F (15C to 30C). This is especially helpful to do when you first start taking new drugs or using a combination of treatments. Can diet help improve depression symptoms? Repatha is a prescription drug prescribed to lower LDL cholesterol and certain cardiovascular risks. Talk with your doctor right away if you have fever or chills with your joint pain. Any time youre considering taking a supplement, its important to discuss this with your doctor or pharmacist. Zetia may not be right for you if you have certain medical conditions or other factors that affect your health. For some drugs, doing so may lead to unwanted side effects or overdose. Other interactions can increase side effects or make them more severe. Lipitor is available in a generic form called atorvastatin. You may not have any symptoms of gallstones unless they cause your gallbladder to swell. Additionally, a change in weight is not a listed side . People with this condition have high levels of plant sterols. Get emergency medical help if you have signs of an allergic reaction to Zetia: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Physicians who treat dysautonomia can be located on our Physician List. Here is a list of conditions that the Food and Drug Administration (FDA) has approved Zetia and Lipitor to treat. Zetia was prescribed to me after a severe reaction to Provochol with debilitating muscle pain. Your risk of developing serious side effects may increase if you take Zetia with other medications to treat high cholesterol, such as statin drugs. Welchol is a prescription drug used to treat type 2 diabetes and high cholesterol. Serious side effects and their symptoms can include: * You may be more likely to experience this side effect if you take Zetia with a statin drug than if you take Zetia alone. If your doctor confirms you had a mild allergic reaction to Zetia, theyll decide if you should continue using it. POTS is a form of "autonomic dysregulation" (a nervous system disorder) in which your heart rate spikes upon standing (among other symptoms). It belongs to a class of drugs called cholesterol absorption inhibitors. These drugs havent been directly compared in clinical studies. Zetia is a brand-name drug that contains the active drug ezetimibe. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Most of these side effects may go away within a few days or a couple of weeks. If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre using Zetia. However, some people have reported experiencing memory loss when taking statin drugs. Youll likely take Zetia once a day. Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. As with most drugs, some people can have an allergic reaction after taking Zetia. Stomach pains were gone after second day. They can both be taken with or without food. Increased liver enzyme levels are a possible side effect of Zetia. For more information on these side effects, see Side effect details below. Currently, no medications have been approved by the FDA to treat POTS. Zetia and Crestor are both brand-name drugs. Using Zetia with medications in the fibrate drug class raises your risk of gallstones even more. It wasnt reported during studies of the drug. Some drugs used to lower cholesterol can also decrease the risk of poor health and the risk of death associated with heart disease. Postural orthostatic tachycardia syndrome (POTS) is a blood circulation disorder characterized by two factors: A specific group of symptoms that frequently occur when standing upright. And Zetia hasnt been shown to affect blood sugar levels in clinical studies of people with diabetes and people without diabetes. Zetia is contraindicated under the following conditions: Zetia tablets should be stored at a room temperature of 77F (25C) in a tightly sealed container away from light. A large review by the American Heart Association compared studies of CoQ10. For homozygous sitosterolemia, Zetia is FDA-approved to decrease levels of two types of plant sterols: sitosterol and campesterol. Postural Tachycardia Syndrome (PoTS) is an abnormality of the autonomic nervous system (ANS). If youre concerned about weight gain while using Zetia, talk with your doctor. Learn about alternatives like new drugs, A new class of self-injectable medications are showing promise in treating high cholesterol. So stopping Zetia may lead to an increase in your cholesterol levels. The cause of the disorder is unknown. Taking Zetia with a statin drug may increase your risk of developing some mild or serious side effects. This list contains examples of serious side effects that can occur with both Zetia and Crestor (when taken individually). There arent any foods that have been specifically reported to interact with Zetia. If you no longer need to take Zetia and have leftover medication, its important to dispose of it safely. Learn more about how grapefruit may interact with medications. Side effects could occur in children who are breastfed by someone taking a statin drug. Crestor is available in a generic form called rosuvastatin. Talk with your doctor if you experience diarrhea while taking this medication. Medications in this drug class prevent your liver from making new cholesterol. Zetia is indicated as an adjunct to a low-cholesterol diet for treatment of the following types of hyperlipidemia: For treatment of primary hyperlipidemia, Zetia is indicated to reduce total cholesterol, low-density lipoprotein (LDL) cholesterol, non-high-density lipoprotein (non-HDL) cholesterol, and apiloprotein B (ApoB). When you get Zetia from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. It also isnt known what percentage of adults and children experienced diarrhea in clinical studies of other conditions treated with Zetia. If your liver function tests show increased liver enzymes called transaminases while youre using Zetia with a statin drug, your doctor may stop your treatment. When this happens, more cholesterol can then be cleared from your blood by your liver. To manage your symptoms, they may suggest an over-the-counter antihistamine you take by mouth, such as Benadryl (diphenhydramine). Legal news and analysis on health care, hospitals, insurers, medical suppliers. The primary symptom of OI is lightheadedness or fainting. Zetia belongs to a class of drugs called cholesterol absorption inhibitors. But in studies, some people had to stop taking the drug due to feeling dizzy. This makes it difficult to keep an upright posture without abnormal heart-rate (tachycardia) and/or sympathetic activity. Sometimes brain zaps are also accompanied by dizziness, pain, or tinnitus, a ringing in the ears. In fact, researchers have looked into using Zetia to treat hair loss due to a condition called alopecia areata. In order to diagnose POTS, your doctor will need to measure your heart rate when you are sitting at rest. If you develop increased liver enzyme levels, your doctor may make changes to your treatment plan. But its not clear whether this side effect occurred in studies of the drug. Ezetimibe can cause the breakdown of muscle tissue . 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